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ฝัณฝฎัฎัั ฒนั นณัณปถั ผปธผ ตฎฏผนณฐฎปถท
ัฎฐปณปถณ ผัถฑถปฎนผฐ ถ ฒดณปณัถธผฐ ฝัผัถฐผผฝัั ผนณฐัั
ััณฒััฐ: ฐ ัณบ ัฎตปถัฎ ถ ฝัถปัถฝ ฒณทััฐถั?
ะปธผนผฑถั โ ััผ ปณ ฝัถฑผฐผั, ถ ฐณฒััถณ ัฝณัถฎนถััั ปณ ัััฎัั ัฐณัฒถัั ผฏ ััผบ. ฎบผณ
ฑนฎฐปผณ โ ัฐผณฐัณบณปปผ ัฎัฝผตปฎปปฎั ฝฎัผนผฑถั, ฎ ัฎธดณ ฝัผทฒณปปฎั ัณัฎฝถั ั ฝัถบณปณปถณบ
ัผฐัณบณปปัั ถ ัััณธัถฐปัั นณธฎัััฐณปปัั ััณฒััฐ. ะผ ฒฎนณธผ ปณ ั ฐัณั ณััั ฐผตบผดปผ ฝผธัฝฎัั
ฒผัผฑถณ ผัถฑถปฎนัปัณ ฝัณฝฎัฎัั. ะ ัฎธผบ ันััฎณ ปฎ ฝผบผัั ฝัถฒัั ฎปฎนผฑถ โ ัฎัับผััถบ ัฎบัณ
ัััณธัถฐปัณ นณธฎัััฐณปปัณ ััณฒััฐฎ, ฐ ัณบ ผันถัถณ ผัถฑถปฎนผฐ ผั ฒดณปณัถธผฐ ถ ฝัผััั
ถปัณัณัปัั ถ ฎธััฎนัปัั ถปัผับฎัถั ผ ฝัณฝฎัฎัฎั .
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ะนฎปถฏ - ัผฐัณบณปปผณ ััณฒััฐผ, ฝัณฒปฎตปฎัณปปผณ ฒนั ฝัผฐณฒณปถั ัณัฎฝถถ ฝฎัถณปัผธ, ั
ธผัผััั ฏัน ผฏปฎััดณป ัฎธ ัฌัปถธผฐ. ะปฎนผฑผบ ฒฎปปผฑผ ฝัณฝฎัฎัฎ ฐััััฝฎณั ะถปฝัฎตฎ, ััผ
ัััณธัถฐปผณ ััณฒััฐผ ั ถฒณปัถัปับ ัผััฎฐผบ. ะัถฑถปฎนัปัท ฝัณฝฎัฎั ฝัผถตฐผฒถั ธผบฝฎปถั
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ัณัถฒถฐ ัฎธฎ ัฌัปถธผฐ;
? ฝัถ ผปธผนผฑถถ บฎัผัปัั ัััฏ;
? ฝณัถัผปณฎนัปัท ัฎธ.
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ฝัผฐณัณปปผท ัฎับฎัณฐัถัณัธผท ธผบฝฎปถณท, ัฌนัฌััั ฎนััณัปฎัถฐปับ ฐฎัถฎปัผบ, ณันถ ั
ฝฎัถณปัธถ ฏันฎ ัััฎปผฐนณปฎ ปณผฝณัฎฏณนัปฎั ัผับฎ ัฎธฎ, ั ปฎนถัถณบ บณัฎััฎต.
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ปณบณนธผธนณัผัปัท ัฎธ นณฑธถั . ัณฒถ ฝผธฎตฎปถท ฝัถัััััฐััั ัฎธถณ ฝฎัผนผฑถถ:
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นณัณปถณ.
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ัผฑผ, ััผ ธฎฝัันั ฐัฝััธฎัััั ฐ ฒฐัั ฒผตถัผฐธฎั โ 40 ถ 80 บฑ. ะณัณฒ ัณบ, ธฎธ Osimert (ะัถบณััถปถฏ 80บฑ) - ะัถบณัั (Osimertinib 80mg) - ฎปฎนผฑ ฎฑัถััผ ธัฝถัั, ัฎธดณ ัถัฎทัณ
ถปััััธัถั โ ผฏฎ นณธฎัััฐฎ ถบณัั ัฐผทััฐผ ฐัตัฐฎัั ฝผฏผัปัณ ัััณธัั.
Ibrutinix (ะฏัััถปถฏ) โ ะฏัััถปถธั (Ibrutinib) - ฎปฎนผฑ ะบฏััฐถธฎ
ะผฐผนัปผ ฝผฝันััปัท ฝัณฝฎัฎั, ธผัผััท ฐัฝััธฎณััั ฐ ฆะ ถ ถบณณั ฏฎัปผันผฐปัั ัณปั โ
ฒฎนณธผ ปณ ธฎดฒผบั ัฎับฎธผนผฑถัณัธผณ ััณฒััฐผ ฝัถฒณััั ฝผ ธฎับฎปั, ผัผฏณปปผ, ณันถ ััถััฐฎัั
ัผั ัฎธั, ััผ ัณัฎฝถั ฒผนดปฎ ฝัผฐผฒถัััั ฐ ัณัณปถณ ฒนถัณนัปผฑผ ฐัณบณปถ.
ะฎ Ibrutinix (ะฏัััถปถฏ) โ ะฏัััถปถธั (Ibrutinib) - ฎปฎนผฑ ะบฏััฐถธฎ ัณปฎ ฑผัฎตฒผ ปถดณ
ฐฐถฒั ัผฑผ, ััผ ััณฒััฐผ ฐััััฝฎณั ฐ ธฎัณััฐณ ฒดณปณัถธฎ. ะัถ ััผบ ั ปณฑผ ถฒณปัถัปัท ัผััฎฐ,
ผฒถปฎธผฐัณ ฝผธฎตฎปถั, ัฎัับผััถบ ถั ฝผฒัผฏปผ:
? นถบัผบฎ;
? บฎธัผฑนผฏันถปณบถั;
? นณทธผต.
ะัถปัถฝ นณัณปถั ัผดณ ถฒณปัถัณป โ ฝถัั ธฎฝัันั ปัดปผ ฐ ผฒปผ ถ ัผ ดณ ฐัณบั, ผฒถป ัฎต ฐ
ัััธถ. ะัถบณัฎัณนัปผ, ััผ บปผฑถณ ฝฎัถณปัั ะบฏััฐถธฎ ฝณัณปผััั ฒฎดณ นณฑัณ, ัณบ ผัถฑถปฎนัปัท
ฝัณฝฎัฎั. ะัผถตฐผฒถััั ััณฒััฐผ ฐ ะฎปฑนฎฒณั, ฐัฝััธผบ ตฎปถบฎณััั ฝัผฐณัณปปฎั ัถับฎ, ธผัผัฎั
ััปธัถผปถััณั ัดณ ฐ ัณัณปถณ ฒนถัณนัปผฑผ ฐัณบณปถ ถ ฒผัผดถั ัฐผณท ัณฝััฎัถณท, ฝผััผบั
ฐัฝััธฎณั ัผนัธผ ัััณธัถฐปัณ ฝัผัถฐผผฝัั ผนณฐัณ นณธฎัััฐฎ.
ะันถ ฐั ตฎถปัณัณัผฐฎปั ฐ ัผบ, ััผฏั Ibrutinix (ะฏัััถปถฏ) โ ะฏัััถปถธั (Ibrutinib) - ฎปฎนผฑ ะบฏััฐถธฎ ธัฝถัั, ัฒณนฎัั ััผ บผดปผ ปฎ ปฎัณบ ัฎทัณ. ะั ฑผัผฐั ฝัณฒผััฎฐถัั ัณััถัถธฎัั
ธฎัณััฐฎ ปฎ ฐัณ นณธฎัััฐฎ, ธผัผััณ ฐั ฐถฒถัณ ปฎ ัฎทัณ, ฝัถ ััผบ บผดณัณ ฏััั ัฐณัณปั:
ัััณธัถฐปผณ, ฏณตผฝฎัปผณ นณธฎัััฐผ ฝัผฒฎณััั ฝผ ปถตธผท ัณปณ โ ฒณัณฐนณ ปณ ปฎทัถ. ะณัณฒ นณัณปถณบ
ปัดปผ ฝัผธผปัันััถัผฐฎัััั ั ผปธผนผฑผบ: ผฏฎ นณธฎัััฐฎ ถบณัั ฝัผัถฐผฝผธฎตฎปถั ธ
ถัฝผนัตผฐฎปถั.
Alecnib (ะนณธัถปถฏ) - ะนณธปถฏ (Alectinib) - ฎปฎนผฑ ะนณัณปัฎ;
ะันถ ั ฝฎัถณปัฎ ฏัน ฒถฎฑปผััถัผฐฎป ฎปฎฝนฎััถัณัธถท ALK-ฝผตถัถฐปัท ัฎธ นณฑธผฑผ, ฝัถ
ััผบ ัณัฎฝถั ั ฝัถบณปณปถณบ ธัถตผัถปถฏฎ ผธฎตฎนฎัั ปณัััณธัถฐปผท, ฐ ัฎธผบ ันััฎณ ฏผนัปผบั
ัณธผบณปฒััั ถัฝผนัตผฐฎปถณ ะนณธัถปถฏฎ โ ผัถฑถปฎนัปัท ฝัณฝฎัฎั, ธผัผััณ ฝผธฎตฎน ั ผัผัถณ
ัณตันััฎัั ฝัถ นณัณปถถ ฝฎัถณปัผฐ ั ผปธผนผฑถณท. ัผถบผััั ผัถฑถปฎนฎ ผัณปั ฐััผธฎั โ
ฝัถฏนถตถัณนัปผ 10ย 000 ั.ณ., ฒฎนณธผ ปณ ธฎดฒัท ฝฎัถณปั บผดณั ฝผตฐผนถัั ัณฏณ ฝัถผฏัณััถ ัฎธถณ
ัฎับฝัณฝฎัฎัั, ผัผฏณปปผ ััถััฐฎั ฒนถัณนัปผััั ัณัฎฝถถ.
ั ณบฎ นณัณปถั ฐ ผฏผถั ันััฎัั ฒผนดปฎ ฏััั ัฎัััถัฎปฎ ฒผธัผัผบ-ผปธผนผฑผบ, ััฎปฒฎััปัท
ฐฎัถฎปั ฝัณฒฝผนฎฑฎณั ฝัถบณปณปถณ 600 บฑ นณธฎัััฐฎ ฒฐฎดฒั ฐ ัััธถ, ฐ ผฒปผ ถ ัผ ดณ ฐัณบั. Alecnib (ะนณธัถปถฏ) - ะนณธปถฏ (Alectinib) - ฎปฎนผฑ ะนณัณปัฎ ธัฝถัั ัณธผบณปฒผฐฎปผ ฝฎัถณปัฎบ, ั ธผัผััั
ฏันฎ ฒถฎฑปผััถัผฐฎปฎ ผปธผนผฑถั, ปผ ฝัณฒฐฎัถัณนัปผ ปณผฏั ผฒถบผ ฐปถบฎัณนัปผ ถตััถัั
ถปััััธัถั ฝผ ฝัถบณปณปถั ฝัณฝฎัฎัฎ.
ะ ฎตปถัฎ บณดฒั ผัถฑถปฎนผบ ถ ฒดณปณัถธผบ ตฎธนััฎณััั ัผนัธผ ฐ ัณปผฐผท ฝผนถัถธณ. ะฏฎ
ฝัณฝฎัฎัฎ ฐัฝััธฎัััั ฝัผฐณัณปปับถ ฝัผถตฐผฒถัณนัฌถ, ธผัผััณ ััฎัณนัปผ ัผฏนัะฮฯั ฐัณ
ปผับั ฝัถ ถตฑผัผฐนณปถถ นณธฎัััฐณปปัั ััณฒััฐ. ัผถั ผับณัถัั, ััผ ั ฒดณปณัถธฎ ผันถัปผณ
ธฎัณััฐผ, ฐ ปณธผัผััั ันััฎัั , ััฒั ฝผ ผัตัฐฎบ, ฎปฎนผฑถัปัณ ฝัณฝฎัฎัั ฝณัณปผััััั ฝฎัถณปัฎบถ
ฒฎดณ นัััณ, ัณบ ผัถฑถปฎนัปัณ. ะตััฎทัณ ถปััััธัถั, ัฎธดณ ฐฎดปผ ธผปัันััถัผฐฎัััั ั
ฒผธัผัผบ ฝณัณฒ ปฎัฎนผบ นณัณปถั ฐผ ถตฏณดฎปถณ ฝผัฌนณปถั ปณฑฎัถฐปัั ฝผันณฒััฐถท ถต-ตฎ
ถปฒถฐถฒัฎนัปผท ปณฝณัณปผัถบผััถ ฎธัถฐปผฑผ ฒณทััฐัััณฑผ ฐณัณััฐฎ นณธฎัััฐฎ. กตปฎัั, ธฎธฎั ั
Alecnib (ะนณธัถปถฏ) - ะนณธปถฏ (Alectinib) - ฎปฎนผฑ ะนณัณปัฎ ัณปฎ ฐั บผดณัณ ั ธผปัันััฎปัผฐ
ธผบฝฎปถถ.
ะผัณบั ฒฎดณ ฐณฒััถณ ผปธผนผฑถ ัณธผบณปฒััั ฝัถผฏัณัฎัั
ฒดณปณัณธถ?
ะัณ นณธฎัััฐฎ-ฒดณปณัถธถ, ธผัผััณ ถบณัั ฝัผัถฐผัฎธผฐผณ ฐผตฒณทััฐถณ ปฎ ผัฑฎปถตบ,
ฝัผถตฐผฒัััั ฐ ะฎปฑนฎฒณัณ. ก ปถั ถบณณััั ฑผััฒฎัััฐณปปฎั ัณฑถัััฎัถั, ธผัผัฎั ฑฎัฎปัถััณั:
นณัณปถณ ฏัฒณั ปณ ัผนัธผ ัััณธัถฐปับ, ปผ ถ ฏณตผฝฎัปับ. ะฎฐผฒ ัฎฏผัฎณั ฐ ัผผัฐณัััฐถถ ัผ
ััฎปฒฎััฎบถ GMP. ะณธฎัััฐฎ ฝผััฎฐนััััั ฐ ะถัฎท, ะตถั, ะปฒถั โ ถ ฐผั ัผฐัณบ ปณฒฎฐปผ
ัปถธฎนัปฎั ฐผตบผดปผััั ฝัถผฏัณััถ ฝัผัถฐผผฝัั ผนณฐัณ ฝัณฝฎัฎัั ฝผัฌถนฎัั ั ัผััถัฌ, ฎ ัฎธดณ
ดถัณนณท ฐัณั ัััฎป ฏัฐัณฑผ ะะ.
ฃผัถัณ ัผัััฒปถัฎัั ั ปฎฒณดปับ, ฝัผฐณัณปปับ ฝผััฎฐัถธผบ โ ผฏัฎัฎทัณัั ปฎ
ผัถัถฎนัปัท ัฎทั ฝัณฒััฎฐถัณนัััฐฎ ฐ ะ ผััถถ velpanex.ru. ะัณ ฒดณปณัถธถ ผฏนฎฒฎัั
ฝัณฐผัั ผฒปับ ธฎัณััฐผบ, ฝผ ฐผตฒณทััฐถั ปฎ ผัฑฎปถตบ ปถัณบ ปณ ผันถัฎัััั ผั ฒผัผฑผััผััถั
ผัถฑถปฎนัปัั นณธฎัััฐ.
ะัถณบนณบฎั ัณปผฐฎั ฝผนถัถธฎ ัฐัฌฎปฎ ั ัณบ, ััผ ฏัณปฒ ปณ ัฎัธัััณป, ฒผััฎฐธฎ ฝัณฝฎัฎัผฐ
ฐัั ผฒถั ฒณัณฐนณ. ะัถ ััผบ ฐัณ ฐััณผฝถัฎปปัณ นณธฎัััฐณปปัณ ััณฒััฐฎ ฝัผัถฐ ผปธผนผฑถัณัธถั
ฝฎัผนผฑถท ผฏนฎฒฎัั ัั ผดถบ ฐผตฒณทััฐถณบ ปฎ ผัฑฎปถตบ, ฝผตฐผนััั ถตฏฎฐถัััั ผั ตนผธฎัณััฐณปปัั
ฝัผัณััผฐ, ฎ ฐ ตฎฝััณปปัั ััฎฒถัั โ ัััณััฐณปปผ ันัััถัั ธฎัณััฐผ ดถตปถ ฝฎัถณปัฎ, ฝัผฒนถัั
ณณ. ะฏัฎัฎทัณัั ปฎ ผัถัถฎนัปัท ัฎทั, ณันถ ตฎถปัณัณัผฐฎปั ฐ ฝผธัฝธณ ธฎัณััฐณปปัั , ฏณตผฝฎัปัั ,
ัััณธัถฐปัั ฝัผัถฐผัฎธผฐัั ััณฒััฐ ฝผ ฎฒณธฐฎัปผท ััผถบผััถ.
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